Liverpool could be without Alexander Isak for their crucial Champions League group-stage clash against Real Madrid, according to respected journalist Paul Joyce of The Times.

The news comes as a major blow for Arne Slot, whose side are already grappling with a growing injury list at a crucial stage of the season.

The Reds host Xabi Alonso’s Real Madrid on Tuesday night in what promises to be another chapter in one of European football’s most storied rivalries.

With both clubs chasing qualification for the Champions League knockout rounds, the fixture carries enormous significance, especially for Liverpool, who suffered a 1-0 defeat to Galatasaray last month that complicated their path to the last 16.

Liverpool could be without Alexander Isak vs Real Madrid

Isak has now missed three consecutive matches after sustaining a groin injury during Liverpool’s 5-1 win over Eintracht Frankfurt two weeks ago.

The Swedish striker was expected to be assessed ahead of the Real Madrid tie, but Joyce reports that his recovery has been slower than anticipated, making him a major doubt for the European clash.

Alexander Isak misses Liverpool training ahead of Real Madrid. Curtis Jones back with group.

— paul joyce (@_pauljoyce) November 3, 2025

In his absence, Hugo...